The Joy of Why播客2024年五月二十三日內容文字版：https://www.quantamagazine.org/what-happens-in-the-brain-to-cause-depression-20240523/
Introduction導言
For decades, the best drug therapies for treating depression, like SSRIs, have been based on the idea that depressed brains don’t have enough of the neurotransmitter serotonin. Yet for almost as long, it’s been clear that simplistic theory is wrong. Recent research into the true causes of depression is finding clues in other neurotransmitters and the realisation that the brain is much more adaptable than scientists once imagined. Treatments for depression are being reinvented by drugs like ketamine that can help regrow synapses, which can in turn restore the right brain chemistry and improve whole body health.In this episode, John Krystal, a neuropharmacologist at the Yale School of Medicine, shares the new findings in mental health research that are revolutionising psychiatric medication.
Listen on Apple Podcasts, Spotify, TuneIn or your favourite podcasting app, or you can stream it from Quanta.
幾十年來，治療抑鬱症的最佳藥物療法，如SSRIs，一直基於抑鬱症大腦沒有足夠的神經遞質血清素的想法。 然而，在幾乎一樣長的時間裡，很明顯，簡單化理論是錯誤的。 最近對抑鬱症真正原因的研究是在其他神經遞質中找到線索，並意識到大腦的適應性比科學家曾經想象的要強得多。 氯胺酮等藥物正在重新發明抑鬱症的治療方法，這些藥物可以幫助突觸再生，這反過來可以恢復右腦化學反應並改善全身健康。
在這一集中，耶魯醫學院的神經藥理學家John Krystal分享了正在徹底改變精神病藥物的心理健康研究的新發現。
在蘋果播客、Spotify、TuneIn或您最喜歡的播客應用程式上收聽，或者您可以從Quanta流媒體播放。